Used primarily in oligonucleotide synthesis, it serves as a protected deoxyguanosine derivative. The trityl group (Trt) protects the 5'-hydroxyl group, while the isobutyryl (iBu) group protects the exocyclic amine, ensuring selective reactivity during the assembly of DNA sequences. This compound is crucial in solid-phase synthesis, enabling the precise construction of custom DNA strands for research, diagnostics, and therapeutic applications, such as antisense oligonucleotides or gene editing tools. Its protective groups are later removed under specific conditions to yield the desired DNA product.