5'-O-DMT-N6-iBu-dA

97%

Reagent Code: #47937
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CAS Number 190834-10-7

science Other reagents with same CAS 190834-10-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 623.71 g/mol
Formula C₃₅H₃₇N₅O₆
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

This chemical is primarily used in the field of oligonucleotide synthesis, particularly in the production of modified DNA strands. It serves as a protected nucleoside monomer, where the 5'-hydroxyl group is protected by a dimethoxytrityl (DMT) group, and the N6 position of the adenine base is protected by an isobutyryl group. This protection strategy allows for controlled and sequential addition of nucleotides during solid-phase synthesis, ensuring high precision in the construction of custom DNA sequences. It is especially valuable in the development of therapeutic oligonucleotides, such as antisense molecules, siRNAs, and aptamers, which are used in gene silencing, targeted therapy, and diagnostic applications. The modifications enhance the stability and specificity of the synthesized oligonucleotides, making them more effective in biological systems.

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Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿4,122.00
inventory 50mg
10-20 days ฿14,400.00

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5'-O-DMT-N6-iBu-dA
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This chemical is primarily used in the field of oligonucleotide synthesis, particularly in the production of modified DNA strands. It serves as a protected nucleoside monomer, where the 5'-hydroxyl group is protected by a dimethoxytrityl (DMT) group, and the N6 position of the adenine base is protected by an isobutyryl group. This protection strategy allows for controlled and sequential addition of nucleotides during solid-phase synthesis, ensuring high precision in the construction of custom DNA sequenc

This chemical is primarily used in the field of oligonucleotide synthesis, particularly in the production of modified DNA strands. It serves as a protected nucleoside monomer, where the 5'-hydroxyl group is protected by a dimethoxytrityl (DMT) group, and the N6 position of the adenine base is protected by an isobutyryl group. This protection strategy allows for controlled and sequential addition of nucleotides during solid-phase synthesis, ensuring high precision in the construction of custom DNA sequences. It is especially valuable in the development of therapeutic oligonucleotides, such as antisense molecules, siRNAs, and aptamers, which are used in gene silencing, targeted therapy, and diagnostic applications. The modifications enhance the stability and specificity of the synthesized oligonucleotides, making them more effective in biological systems.

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