Used in organic synthesis as a protected nucleoside intermediate, particularly in the preparation of modified RNA or DNA analogs. The compound's silyl-protected structure stabilizes the sugar moiety during phosphoramidite-based oligonucleotide assembly, making it valuable in antisense technology and therapeutic oligonucleotide development. Its steric bulk helps reduce side reactions during coupling steps in solid-phase synthesis. Also employed in the study of nucleic acid enzymes due to its resistance to premature deprotection under mild acidic conditions.