N-[1-[(2R,6S)-6-(Hydroxymethyl)-4-tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide
95%
science Other reagents with same CAS 125515-31-3
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description Product Description
This compound is a protected morpholino-pyrimidine nucleoside analog, serving as a key intermediate in the synthesis of morpholino antisense oligonucleotides (PMOs). PMOs are widely used in pharmaceutical research for gene modulation, particularly in exon-skipping therapies for genetic disorders such as Duchenne Muscular Dystrophy (DMD). The trityl group provides protection during oligonucleotide assembly, while the benzamide substituent stabilizes the pyrimidine base, enhancing synthetic efficiency and purity in targeted therapeutic development.
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