Used as an intermediate in the synthesis of oligonucleotides, particularly in the preparation of modified RNA strands for research and therapeutic applications. Its primary role is in the development of antisense oligonucleotides and small interfering RNA (siRNA) where selective protection of the 2'-hydroxyl group enhances stability and specificity during solid-phase synthesis. The tert-butyldimethylsilyl group provides steric protection, while the N-benzoyl moiety stabilizes the cytosine base, minimizing side reactions. This compound is essential in producing nucleic acid analogs with improved nuclease resistance and binding affinity, useful in gene silencing and molecular biology studies.