2-Deoxy-2-fluoro-alpha-D-arabinofuranosyl bromide 3,5-dibenzoate
98%
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description Product Description
Used as a key intermediate in the synthesis of nucleoside analogs, particularly in the preparation of antiviral and anticancer agents. Its fluorinated sugar moiety enables enhanced metabolic stability and improved binding affinity to target enzymes. Commonly employed in glycosylation reactions to construct fluorinated nucleosides, such as those found in certain antiviral drugs like fluorinated analogs of vidarabine or related compounds. The dibenzoate groups act as protecting groups, allowing selective reactivity at specific hydroxyl positions during stepwise synthesis. Widely utilized in medicinal chemistry for the development of modified nucleic acid therapeutics and probes for biochemical studies.
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