2'-Deoxy-2'-fluorouridine
98.0%
Reagent
Code: #126923
Alias
2'-Fluoro-2'-deoxyuridine
CAS Number
784-71-4
blur_circular Chemical Specifications
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Molecular Information
Weight
246.19 g/mol
Formula
C₉H₁₁FN₂O₅
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Registry Numbers
MDL Number
MFCD01317293
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Storage & Handling
Storage
room temperature
description Product Description
Used primarily in the development of antiviral drugs, particularly for treating RNA virus infections. It serves as a nucleoside analog that inhibits viral replication by incorporating into viral RNA, causing chain termination. This mechanism is crucial in the treatment of diseases caused by viruses like hepatitis C and certain respiratory viruses. Additionally, it is researched for its potential in cancer therapy, where it can disrupt the synthesis of DNA in rapidly dividing cancer cells. Its fluorinated structure enhances its stability and bioavailability, making it a valuable component in medicinal chemistry.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Melting Point | 147-153 |
| Purity (HPLC) | 97.5-100 |
| Purity (Neutralization Titration) | 95-100% |
| Specific Rotation [α]20/D (C=0.3, H2O) | 50-56 |
| Appearance | White To Off-White Powder Or Crystals |
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