DNA-Grade Guanidine Thiocyanate Solution is used extensively in molecular biology for the isolation and purification of DNA from cells and tissues. It effectively disrupts cell walls and nuclear membranes, releasing DNA into solution while protecting it from degradation by nucleases. Commonly employed in DNA extraction protocols, it facilitates the separation of DNA from proteins and other contaminants. Additionally, it is utilized in the preparation of samples for downstream applications, including PCR, cloning, and DNA sequencing. Its chaotropic properties ensure high-purity, intact DNA, making it a crucial reagent in genetic research and diagnostics.