LE 135 is primarily utilized in research settings, particularly in the study of nuclear receptors and their signaling pathways. It is known to act as an antagonist for certain nuclear receptors, making it a valuable tool in understanding receptor function and regulation. Researchers use LE 135 to investigate the mechanisms of gene expression, cellular differentiation, and metabolic processes. Its application extends to the development of potential therapeutic agents targeting nuclear receptor-related diseases, such as metabolic disorders, cancer, and hormonal imbalances. By blocking specific receptor activities, LE 135 helps elucidate the roles of these receptors in physiological and pathological conditions, contributing to advancements in biomedical science.