Nociceptin, also known as Orphanin FQ, is primarily studied for its role in the central nervous system, where it acts as a neurotransmitter or neuromodulator. It is involved in regulating various physiological processes, including pain perception, anxiety, stress responses, and reward pathways. Research has explored its potential as a target for developing analgesics, particularly for managing chronic pain, as it modulates pain signals without the side effects associated with traditional opioids. Additionally, it is being investigated for its role in treating anxiety and depression, given its influence on mood regulation. In the field of addiction research, Nociceptin is studied for its ability to modulate drug-seeking behavior, offering potential therapeutic avenues for substance abuse disorders. Its diverse roles in the brain make it a promising candidate for various neurological and psychiatric applications.