1-Fluoro-3-iodo-5-nitrobenzene
98%
Reagent
Code: #187494
CAS Number
3819-88-3
blur_circular Chemical Specifications
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Molecular Information
Weight
267.00 g/mol
Formula
C₆H₃FINO₂
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Registry Numbers
MDL Number
MFCD00007219
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Physical Properties
Melting Point
77-79 °C (Lit.)
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions where selective functionalization of aromatic rings is required. Its combination of fluorine, iodine, and nitro groups allows for sequential cross-coupling reactions, making it valuable in the development of complex organic molecules. Commonly employed in the preparation of active ingredients in crop protection agents and in medicinal chemistry for building blocks of drug candidates. The electron-withdrawing nitro and fluoro groups enhance reactivity in nucleophilic aromatic substitution, while the iodo group facilitates palladium-catalyzed coupling reactions such as Suzuki or Heck reactions.
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