tert-butyl (2E/Z)-4,4,4-trifluoro-3-(3-nitrophenyl)but-2-enoate

Reagent Code: #181172
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CAS Number 1297551-38-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 317.265 g/mol
Formula C₁₄H₁₄F₃NO₄
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated active pharmaceutical ingredients (APIs). The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity, which can improve drug absorption and bioavailability. The nitrophenyl moiety allows for further functionalization through reduction or coupling reactions, enabling the construction of complex molecular architectures. Its ester group serves as a protecting group or can be hydrolyzed to yield carboxylic acid derivatives for conjugation. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its rigid, conjugated structure and electronic properties.

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inventory 1g
10-20 days ฿22,800.00

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