4-Hydroxy-2'-nitrobiphenyl
≥97%(GC)
Reagent
Code: #195098
CAS Number
51264-59-6
blur_circular Chemical Specifications
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Molecular Information
Weight
215.21 g/mol
Formula
C₁₂H₉NO₃
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Registry Numbers
MDL Number
MFCD00143326
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Physical Properties
Melting Point
115°C
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Storage & Handling
Storage
Room temperature, dryness, inert gas storage
description Product Description
Used primarily as an intermediate in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), particularly in the production of loxoprofen and related prodrugs. Its structure allows for functional group modifications that are key in developing active pharmaceutical ingredients with improved bioavailability and targeted activity. The nitro group facilitates reduction to an amine, enabling further derivatization, while the hydroxyl group can be used for esterification or ether formation. It is also employed in research settings for developing biphenyl-based compounds with potential biological activity.
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