(S)-3-(1-Aminoethyl)-4-fluorobenzonitrile hydrochloride
95%
Reagent
Code: #233397
CAS Number
2703745-55-3
blur_circular Chemical Specifications
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Molecular Information
Weight
200.64 g/mol
Formula
C₉H₁₀ClFN₂
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Registry Numbers
MDL Number
MFCD33404999
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Used as a key chiral intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the production of selective serotonin reuptake inhibitors (SSRIs) and other central nervous system agents. Its fluorinated aromatic structure combined with a chiral amine functionality makes it valuable for enhancing metabolic stability and binding selectivity in drug candidates. Commonly employed in asymmetric synthesis routes where the (S)-enantiomer provides optimal biological activity. Also utilized in the development of radiolabeled compounds for positron emission tomography (PET) imaging due to the presence of fluorine, enabling direct incorporation of F-18 in some labeling strategies.
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