4-Fluoro-3-iodobenzonitrile
98%
Reagent
Code: #189619
CAS Number
159719-57-0
blur_circular Chemical Specifications
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Molecular Information
Weight
247.01 g/mol
Formula
C₇H₃FIN
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Registry Numbers
MDL Number
MFCD08458123
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Storage & Handling
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure allows for selective cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex aromatic systems. Commonly employed in Suzuki and Buchwald–Hartwig reactions to introduce fluorinated and iodinated aromatic motifs, which can enhance metabolic stability and binding affinity in drug candidates. Also utilized in the preparation of radiolabeled compounds for positron emission tomography (PET) imaging due to the presence of iodine, which can be substituted with radioactive isotopes.
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