Used primarily in pharmaceutical research as a potent and selective agonist for nicotinic acetylcholine receptors, particularly the α4β2 subtype. This compound shows promise in the development of treatments for neurological disorders such as depression, anxiety, and cognitive impairment. Its structure allows for high blood-brain barrier penetration, making it effective in central nervous system applications. It has also been studied for potential use in smoking cessation therapies due to its modulatory effects on neurotransmitter release. The fumarate salt form enhances stability and bioavailability, which supports its use in preclinical and clinical formulations.