2-Chloro-N'-hydroxynicotinimidamide
97%
Reagent
Code: #156874
CAS Number
468068-58-8
blur_circular Chemical Specifications
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Molecular Information
Weight
171.59 g/mol
Formula
C₆H₆ClN₃O
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Registry Numbers
MDL Number
MFCD08273500
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as an intermediate in the synthesis of nicotinic acetylcholine receptor (nAChR) modulators, particularly in the development of compounds targeting neurological disorders such as Alzheimer's and Parkinson's disease. It serves as a key building block in agrochemical research for creating novel neonicotinoid insecticides with improved selectivity and lower environmental impact. Its hydroxylamine functionality allows for efficient coupling reactions, enabling rapid derivatization in medicinal chemistry campaigns. Also employed in the preparation of radiolabeled probes for receptor binding studies due to its high affinity for central nervous system targets.
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