Methyllycaconitine citrate is primarily utilized in scientific research as a selective antagonist for nicotinic acetylcholine receptors, particularly the α7 subtype. Its application is crucial in neuropharmacology studies to understand the role of these receptors in the central nervous system. Researchers use it to investigate mechanisms underlying cognitive functions, memory, and neurological disorders such as Alzheimer's disease and schizophrenia. Additionally, it serves as a tool compound in electrophysiology experiments to block specific receptor activity, aiding in the exploration of synaptic transmission and neuronal signaling pathways. Its high specificity makes it valuable for dissecting the contributions of α7 receptors in various physiological and pathological processes.