Chloro(4-cyanophenyl)[(R)-1-[(S)-2-(dicyclohexylphosphino)ferrocenyl]ethyldiphenylphosphine]nickel(II)
≥95%
science Other reagents with same CAS 2049086-36-2
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Used as a chiral nickel-based catalyst in asymmetric synthesis, particularly in enantioselective cross-coupling reactions. It enables the formation of carbon-carbon bonds with high stereoselectivity, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. Its phosphine ligands provide steric bulk and electronic tuning that enhance catalytic activity and enantiocontrol. Commonly applied in Kumada, Negishi, and Suzuki-type couplings where precise stereochemistry is required. Stable under inert conditions and effective at low catalyst loadings, it is suited for industrial-scale asymmetric transformations.
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