Chloro(4-cyanophenyl)(R)-1-[(S)-2-(dicyclohexylphosphino)ferrocenyl]ethyl(dicyclohexylphosphine)nickel(II)
science Other reagents with same CAS 2049086-35-1
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Used as a chiral nickel-based catalyst in asymmetric synthesis, particularly in enantioselective cross-coupling reactions. It enables the formation of carbon–carbon bonds with high stereocontrol, making it valuable in the synthesis of optically active compounds such as pharmaceuticals and fine chemicals. Its ferrocenyl backbone and phosphine ligands enhance stability and promote efficient catalytic activity under mild conditions. Commonly applied in Kumada and Negishi couplings where precise chirality transfer is required.
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