BAY 11-7085 is widely used in biomedical research as a potent and selective inhibitor of NF-κB activation. It is particularly valuable in studying inflammation, immune responses, and cancer, as it effectively blocks the signaling pathway that regulates these processes. Researchers utilize it to explore the role of NF-κB in cellular responses to stress, cytokines, and pathogens. Additionally, it aids in understanding the molecular mechanisms underlying diseases like rheumatoid arthritis, atherosclerosis, and certain cancers. Its application extends to in vitro and in vivo studies, providing insights into potential therapeutic strategies targeting NF-κB-related pathways.