AP-1/NF-κB activation inhibitor 1 is primarily utilized in research settings to study cellular signaling pathways, particularly those involving inflammation, immune response, and cancer. It effectively suppresses the activation of AP-1 and NF-κB transcription factors, which play crucial roles in regulating genes associated with inflammation, cell proliferation, and survival. This inhibitor is instrumental in understanding the molecular mechanisms underlying diseases like arthritis, autoimmune disorders, and various cancers. Additionally, it aids in the development of therapeutic strategies targeting these pathways, offering potential for novel treatments in inflammatory and oncological conditions. Its application extends to preclinical studies, where it helps evaluate the efficacy of targeting AP-1 and NF-κB in disease models.