IMD-0560 is primarily known for its role as an inhibitor of IKKβ, a key enzyme in the NF-κB signaling pathway. This pathway is involved in regulating inflammation, immune responses, and cell survival. By inhibiting IKKβ, IMD-0560 has shown potential in reducing inflammation and is being studied for its therapeutic applications in various inflammatory diseases. Research has explored its use in conditions such as rheumatoid arthritis, where excessive inflammation leads to joint damage. Additionally, IMD-0560 has been investigated for its potential in treating certain cancers, as the NF-κB pathway is often dysregulated in tumor cells, promoting their survival and proliferation. Its ability to modulate this pathway makes it a promising candidate for further development in both anti-inflammatory and anti-cancer therapies.