Used primarily in scientific research as a potent and selective antagonist for the neurokinin-1 (NK1) receptor, which plays a role in regulating substance P-mediated signaling. This compound is valuable in studies related to pain transmission, inflammation, depression, and nausea, particularly in exploring central nervous system disorders. Its high selectivity allows researchers to investigate the specific role of NK1 receptors without significant off-target effects, making it a useful pharmacological tool in neuropharmacology and behavioral studies. Due to its research-grade nature, it is not used in clinical or therapeutic settings but supports the development of novel drugs targeting neurokinin pathways.