4-Chloro-2-(cyclopropylmethoxy)-N-(3-fluoro-4-methoxybenzyl)nicotinamide
≥95%
Reagent
Code: #162929
CAS Number
1629615-99-1
blur_circular Chemical Specifications
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Molecular Information
Weight
364.8 g/mol
Formula
C₁₈H₁₈ClFN₂O₃
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of suvorexant, a dual orexin receptor antagonist prescribed for the treatment of insomnia. Its structure enables selective binding to orexin receptors, helping regulate wakefulness. Due to its specific substitution pattern, it contributes to the metabolic stability and blood-brain barrier penetration of the final drug substance. Widely utilized in pharmaceutical research and development for sleep disorder therapeutics.
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