Used as a potent and selective antagonist for the GPR55 receptor, making it a valuable tool in pharmacological research focused on the endocannabinoid system. It helps investigate signaling pathways linked to pain, inflammation, and metabolic disorders. Due to its high selectivity, it is employed in studies to differentiate GPR55-mediated effects from those involving classical cannabinoid receptors CB1 and CB2. Commonly used in in vitro assays and animal models to explore the role of GPR57 in neurodegenerative diseases, cancer progression, and immune regulation.