LY243246 is a selective antagonist of metabotropic glutamate receptors (mGluR2/3), primarily utilized in the field of medical research, particularly in studies related to neuroscience and pharmacology. It is often employed as a tool compound to investigate the mechanisms of certain neurological pathways and receptors. Researchers use it to explore its potential effects on brain function and behavior, which can provide insights into the development of treatments for neurological and psychiatric disorders such as schizophrenia, anxiety, and depression. Its application is crucial in preclinical studies aimed at understanding the modulation of specific neurotransmitter systems, which could lead to the discovery of novel therapeutic agents.