Fezolinetant is primarily used in the treatment of moderate to severe vasomotor symptoms associated with menopause, such as hot flashes and night sweats. It works by acting as a neurokinin 3 (NK3) receptor antagonist, which helps regulate the body's temperature control mechanisms. This makes it a non-hormonal alternative for women who cannot or prefer not to use hormone replacement therapy. Its targeted action provides relief from disruptive symptoms, improving quality of life for menopausal women.