Rehmannioside C is primarily used in traditional medicine and modern herbal formulations for its potential anti-inflammatory and neuroprotective effects. It has been studied for its role in supporting cognitive health, particularly in models of neurodegenerative conditions such as Alzheimer’s disease. The compound may help modulate oxidative stress and reduce neuronal damage due to its antioxidant properties. It is also investigated for its ability to regulate immune responses and support kidney and liver function in herbal medicine systems. Ongoing research explores its potential in managing diabetes-related complications by influencing glucose metabolism and protecting tissue damage caused by prolonged hyperglycemia.