Liriodendrin is primarily studied for its biological activities, especially in the field of natural product-based medicine. It exhibits notable anti-inflammatory and neuroprotective effects, making it a compound of interest in research related to neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Studies suggest it may help reduce oxidative stress and inhibit the activation of inflammatory pathways in neural tissues. Additionally, it has been found to help lower blood sugar levels, suggesting potential applications in supporting the treatment of diabetes.

It also shows potential in bone health, where it has been investigated for its ability to promote osteoblast differentiation and bone formation, indicating possible applications in treating osteoporosis. Additionally, liriodendrin has demonstrated antiviral and anticancer properties in preliminary in vitro studies, particularly in suppressing the proliferation of certain tumor cell lines.

Due to its origin from medicinal plants, it is often explored as a bioactive marker compound in herbal formulations, especially in traditional medicines used for treating liver disorders and inflammatory conditions. However, most applications remain in the preclinical research stage, requiring further validation for therapeutic use.