Dehydroeffusol is a natural phenanthrene compound primarily recognized for its biological activity, particularly in traditional medicine applications. It exhibits notable anti-inflammatory properties by inhibiting enzymes such as cyclooxygenase (COX) and lipoxygenase (LOX), as well as suppressing microglial cell activation to reduce pro-inflammatory mediators like nitric oxide and cytokines involved in chronic neuroinflammation. These effects make it a compound of interest in developing treatments for neurological disorders such as Alzheimer’s and Parkinson’s disease.

It also demonstrates antioxidant effects by scavenging free radicals, helping to protect cells from oxidative stress. This property is beneficial in pharmaceutical, cosmetic formulations aimed at slowing cellular aging, and preventing damage from environmental stressors.

Additionally, dehydroeffusol has shown antimicrobial activity against certain pathogens, suggesting potential use in topical antiseptics or supportive treatments for infections. Emerging research highlights its anti-cancer potential, particularly against liver and lung cancer cells, through mechanisms like inducing apoptosis and inhibiting abnormal cell proliferation, positioning it as a promising lead for future drug development.

Its natural origin from plants like Juncus effusus and low toxicity profile further support applications in herbal medicine and functional health products.