Alstoyunine E is primarily investigated for its potential neuroprotective properties. It has shown activity in modulating neuronal signaling pathways, making it a candidate for research in neurodegenerative disorders such as Alzheimer's and Parkinson’s disease. Studies suggest it may help reduce oxidative stress in brain tissues and inhibit the aggregation of misfolded proteins linked to cognitive decline. Additionally, it exhibits anti-inflammatory effects in neural environments, which could support its use in developing therapies for brain injury or stroke recovery. Due to its natural origin and structural complexity, it also serves as a lead compound in designing novel bioactive molecules for central nervous system targeting.