Polygalasaponin V is primarily utilized in traditional medicine for its neuroprotective and anti-inflammatory properties. It is often incorporated into herbal formulations aimed at enhancing cognitive function and alleviating symptoms of neurodegenerative disorders such as Alzheimer's disease. Additionally, it is studied for its potential to reduce oxidative stress and improve memory retention. In modern pharmacology, it is explored as a natural compound for developing therapeutic agents targeting mental health and neurological conditions. Its application also extends to research on its anti-cancer properties, where it is investigated for its ability to inhibit tumor growth and induce apoptosis in cancer cells.