AZD 9272 is a potent and selective positive allosteric modulator of the adenosine A2A receptor, primarily investigated for its applications in neurological research, particularly in the study of Parkinson's disease and other neurodegenerative disorders. It modulates adenosine signaling in the brain, which interacts with dopamine pathways, making it a valuable tool for understanding the mechanisms underlying conditions such as Parkinson's disease and potentially Alzheimer's disease. Researchers utilize AZD 9272 to explore its effects on receptor binding and signaling pathways, providing insights into the development of therapeutic strategies. Its application is largely confined to preclinical studies, where it helps in evaluating the efficacy and safety of novel treatments targeting neurological conditions.