Meclofenoxate hydrochloride is primarily used in the treatment of cognitive disorders and memory enhancement. It is often prescribed for conditions such as Alzheimer's disease, dementia, and age-related cognitive decline. The compound works by improving brain metabolism and increasing the utilization of glucose in the brain, which helps in enhancing mental clarity and focus.

In addition to its cognitive benefits, it is also used to alleviate symptoms of fatigue and to improve overall mental performance in individuals experiencing mental strain or stress. It has been found to be particularly effective in elderly patients, helping to restore some level of cognitive function and improve quality of life.

Furthermore, meclofenoxate hydrochloride is sometimes used in the management of stroke recovery, aiding in the rehabilitation process by supporting neural repair and improving neurological outcomes. Its neuroprotective properties make it a valuable component in therapeutic strategies aimed at mitigating brain damage and promoting recovery in various neurological conditions.