Heishuixiecaoline A exhibits significant anti-inflammatory and neuroprotective properties, making it a promising candidate for the development of therapeutics targeting neurodegenerative diseases such as Alzheimer's and Parkinson’s. It has demonstrated the ability to cross the blood-brain barrier efficiently, enhancing its potential for central nervous system applications. In preclinical studies, it modulates key signaling pathways involved in oxidative stress and neuronal apoptosis, particularly through the suppression of pro-inflammatory cytokines and inhibition of microglial activation. Additionally, its structural features support interaction with specific neural receptors associated with cognitive function, suggesting utility in improving memory and learning deficits. Research is ongoing to evaluate its efficacy in animal models of stroke and traumatic brain injury.