Epiallopregnanolone is a neuroactive steroid and the 3β-epimer of allopregnanolone. It functions primarily as a negative allosteric modulator of GABA_A receptors, which can reduce GABAergic inhibition in the brain. This mechanism is being studied for its potential therapeutic effects in psychiatric and neurological disorders, including depression, anxiety, and post-traumatic stress disorder (PTSD), where it may promote wakefulness, improve mood, and counteract excessive sedation. Research also investigates its neuroprotective properties for conditions such as epilepsy and neurodegenerative diseases, as well as its involvement in hormone regulation to address related imbalances. Clinical studies continue to assess its safety, efficacy, and specific applications.