Trofinetide is primarily used in the treatment of Rett syndrome, a rare genetic neurological disorder that predominantly affects females. It works by reducing inflammation and supporting synaptic function in the brain, which helps alleviate some of the symptoms associated with the condition. Patients taking trofinetide may experience improvements in breathing patterns, motor skills, and social interactions. It is often prescribed as part of a comprehensive treatment plan that includes physical therapy, occupational therapy, and other supportive measures. Clinical trials have shown that trofinetide can enhance the quality of life for individuals with Rett syndrome by addressing core symptoms and slowing disease progression.