Porcine dynorphin A(1-13) is primarily used in research settings to study the physiological and pharmacological effects of dynorphins, which are a class of opioid peptides. It is particularly valuable in neuroscience for investigating the role of the kappa-opioid receptor (KOR) in pain modulation, stress responses, and addiction. Researchers utilize this fragment to explore its potential in altering pain perception and its involvement in neuroprotective mechanisms. Additionally, it serves as a tool in understanding the biochemical pathways and signaling cascades associated with dynorphin activity in the central nervous system. Its application extends to studies on mood disorders, such as depression and anxiety, where dynorphin systems are implicated. This peptide is also used in preclinical studies to develop novel therapeutic agents targeting the kappa-opioid receptor for pain management and neurological conditions.