Used in research to investigate the role of Substance P fragments, particularly the N-terminal 1-7 sequence, in modulating neurokinin-1 (NK1) receptor activity, pain signaling, inflammation, and stress responses. Unlike full-length Substance P, which is a potent NK1 agonist, the 1-7 fragment exhibits lower receptor affinity and is commonly applied in cell culture and in vivo models to study anti-nociceptive effects, receptor desensitization, and alternative pathways in nociception and neurotransmission. Also utilized in assays to measure interactions with neuronal and immune cells, including binding kinetics and downstream signaling. Its formulation as a stable trifluoroacetate salt supports consistent results and long-term storage in neuroscience, pharmacology, and immunology studies.