Used in the management of severe chronic pain, particularly in patients who require intrathecal analgesic therapy due to inadequate pain control with systemic medications. It acts as a potent blocker of N-type voltage-gated calcium channels, inhibiting the release of pain-related neurotransmitters in the spinal cord. Due to its targeted mechanism, it is employed in cases of intractable pain associated with cancer, neuropathic conditions, and other severe pain states. Administered via intrathecal infusion, it offers an alternative for patients intolerant to or unresponsive to opioids, often allowing for reduced opioid dosage and associated side effects.