Used in research settings as a potent and selective antagonist for the orexin OX2 receptor, TC-N 1752 is primarily applied in studies related to sleep-wake regulation, narcolepsy, and other neurological disorders linked to the orexin system. It enables scientists to probe the functional roles of OX2 receptor signaling in animal models, helping to clarify the mechanisms behind sleep disorders and evaluate potential therapeutic pathways. Due to its selectivity, it serves as a valuable tool compound in pharmacological assays and central nervous system drug development.