3,7,7-Trimethyl-4-(pyridin-3-yl)-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one
98%
Reagent
Code: #244116
CAS Number
748145-19-9
blur_circular Chemical Specifications
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Molecular Information
Weight
308.383 g/mol
Formula
C₁₈H₂₀N₄O
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Storage & Handling
Storage
-20°C
description Product Description
Used in pharmaceutical research as a potent and selective antagonist of the orexin receptor system, particularly targeting OX1 and OX2 receptors. This compound shows promise in the study of sleep disorders such as insomnia due to its ability to modulate wakefulness and sleep regulation. It serves as a key scaffold in developing central nervous system agents, especially for conditions involving disrupted sleep-wake cycles. Its structural properties allow for high blood-brain barrier penetration, making it valuable in preclinical studies for evaluating orexin pathway involvement in addiction, anxiety, and metabolic regulation.
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