Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structural features enable modulation of metabolic stability and membrane permeability, making it valuable in optimizing drug candidates. Commonly employed in medicinal chemistry for introducing lipophilic, sterically hindered groups that enhance binding selectivity and resistance to enzymatic degradation. Also utilized in the preparation of protease inhibitors and receptor antagonists due to its favorable conformational properties.