TR-14035 is primarily used in research settings as a selective antagonist for the cholecystokinin (CCK) receptor subtype CCK-B. It plays a key role in studies related to anxiety, panic disorders, and gastrointestinal function due to its ability to modulate CCK signaling in the central nervous system. Its high selectivity makes it a valuable tool for investigating the physiological and pathological roles of CCK-B receptors without significant cross-reactivity with CCK-A receptors. It is also utilized in neuropharmacological studies to explore potential anxiolytic and antidepressant mechanisms.