Salsolinol is primarily studied for its role in neurological processes and its potential implications in neurodegenerative diseases. It has been associated with the pathophysiology of Parkinson’s disease, where it may contribute to dopaminergic neuron damage through the formation of neurotoxic derivatives. Researchers investigate salsolinol as a possible biomarker for oxidative stress and dopamine metabolism abnormalities.

It also interacts with opioid receptors and has been linked to the mechanisms underlying alcohol dependence, making it a focus in addiction research. Some studies suggest salsolinol may influence the brain’s reward system, particularly in relation to ethanol consumption.

Additionally, salsolinol exhibits antioxidant properties in certain contexts, although its overall effect in the brain appears to be a complex balance between neuroprotection and neurotoxicity. Due to its presence in the human brain and cerebrospinal fluid, it remains a compound of interest in neuropsychiatric and neuropharmacological studies.