SNX-482 is primarily used in neuroscience research to study ion channel function, particularly the role of R-type voltage-gated calcium channels (Cav2.3). It acts as a selective blocker of these channels, allowing researchers to isolate and examine their contributions to cellular signaling, neurotransmitter release, and neuronal excitability. Due to its high specificity, SNX-482 is a valuable tool in investigating calcium-dependent processes in the central nervous system and in models of neurological disorders such as epilepsy, pain, and neurodegeneration. It is also used in electrophysiological studies to dissect complex calcium channel currents in native tissues and heterologous expression systems.