IPAG(1-(4-iodophenyl)-3-(2-adamantyl)guanidine)
98%
Reagent
Code: #201053
CAS Number
193527-91-2
blur_circular Chemical Specifications
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Molecular Information
Weight
395.29 g/mol
Formula
C₁₇H₂₂IN₃
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Storage & Handling
Storage
Room temperature
description Product Description
Used primarily in scientific research as a radiolabeled compound, particularly when labeled with iodine-125 (¹²⁵I). It serves as a high-affinity probe for studying sigma receptors in the central nervous system. Due to its selective binding to sigma-1 receptors, it is employed in receptor binding assays to characterize receptor distribution, density, and pharmacology in brain tissue. Its adamantyl and iodo-substituted phenyl groups contribute to strong lipophilicity and blood-brain barrier penetration, making it valuable for neuropharmacological studies. Also used in autoradiography to map sigma receptor locations in neural tissues. Not intended for therapeutic use.
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