Used primarily in research and development of pain management therapies due to its ability to activate TRPV1 receptors, which are involved in the perception of heat and pain. It is also utilized in the formulation of topical analgesics for conditions such as arthritis, neuropathy, and muscle pain. Its potent sensory effects make it valuable in studies related to desensitization of nerve endings. Additionally, it serves as a reference compound in analytical testing of capsaicinoids in pharmaceuticals and natural products.