Demethoxyfumitremorgin C
95%
Reagent
Code: #175492
CAS Number
111768-16-2
blur_circular Chemical Specifications
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Molecular Information
Weight
349.426 g/mol
Formula
C₂₁H₂₃N₃O₂
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Registry Numbers
MDL Number
MFCD08544341
thermostat
Physical Properties
Boiling Point
617.8±55.0℃ at 760 mmHg
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Storage & Handling
Density
1.3±0.1g/ml
Storage
2-8℃
description Product Description
Used as a research compound in neuroscience, pharmacology, and stem cell biology, particularly for studying the blood-brain barrier, multidrug resistance proteins, and stem cell populations. It acts as an inhibitor of breast cancer resistance protein (BCRP/ABCG2), which is highly expressed in stem cells and contributes to drug efflux mechanisms in cancer cells. This makes it valuable in experiments aimed at improving drug delivery to the brain, enhancing the efficacy of chemotherapeutic agents, isolating and identifying stem cell populations, and evaluating transporter functions in vitro using cell lines.
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